Affinity chromatography media, MabSelect SuRe™

Fournisseur: Cytiva
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MabSelect SuRe™
17-5438-01EA 3830 EUR
17-5438-01 17-5438-02
Affinity chromatography media, MabSelect SuRe™
Milieux de purification des protéines
MabSelect SuRe™ is composed of a rigid, high-flow agarose matrix and alkali-tolerant rProtein A ligand. The ligand has been engineered to provide greater stability than conventional protein A-based media in the alkaline conditions used in CIP protocols. This enhanced alkali stability improves process economy and product quality.

  • Alkali-stabilised rProtein A ligand withstands rigorous CIP and sanitisation procedures with 0,1 to 0,5 M NaOH, reducing the risk of product contamination and carryover
  • Ligand design gives enhanced protease resistance resulting in lower ligand leakage
  • Generic elution conditions for different MAbs enables platform approach to purification
  • Improves product quality and reduces overall costs
  • Maintained capacity prolongs media lifetime
  • High dynamic binding capacity decreases the amount of medium required
  • High flow agarose matrix allows the processing of large feed volumes

Cleaning can be performed with established, effective, and low-cost reagents such as sodium hydroxide. The medium is suitable for both regular production and clinical phases/process development.
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