1,1-Dimethylbiguanide hydrochloride, white powder

Marques : MP Biomedicals
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ICNA0215780580EA 1199 EUR
ICNA0215780580 ICNA0215780525
1,1-Dimethylbiguanide hydrochloride, white powder
1,1-Dimethylbiguanide hydrochloride

1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.

1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics.

Soluble in water (100 mg/ml - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform.

Formule: C₄H₁₂ClN₅
Poids moléculaire: 165,625 g/mol
Point de fusion: 214…224 °C
Température de stockage: Température ambiante
Numéro MDL: MFCD00012582
Numéro CAS: 1115-70-4

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Résultats des tests de spécification

Identity Test Passes
FTIR Conforms to Standard
Melting Point 214 - 224 °C

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