Sirtinol ≥97% (par RMN)
Marques : Enzo Life SciencesTotal Evaluation: 0
Moyenne des Notes : 0.0 sur 5
SIRT inhibitor
Specific cell permeable inhibitor of the sirtuin family of NAD-dependent deacetylases (ySir2: IC50=48µM; hSIRT1: IC50=60µM; hSIRT2: IC50=58µM) with no effect on human HDAC1. Reported to inhibit Sir2p transcriptional silencing activity in vivo (IC50=25µM) and NAD-dependent histone deacetylase activity of purified recombinant yeast Sir2p (IC50=70µM) and hSIRT2 (IC50=40µM) in vitro.
Formule:
C₂₆H₂₂N₂O₂ Poids moléculaire: 394,46 g/mol |
Numéro CAS:
410536-97-9 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...