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Sirtinol ≥97% (par RMN)

Marques : Enzo Life Sciences
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Total Evaluation: 0
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ALEXALX270308M001EA 63.5 EUR
ALEXALX270308M001 ALEXALX270308M005
Sirtinol ≥97% (par RMN)
Sirtinol

SIRT inhibitor


Specific cell permeable inhibitor of the sirtuin family of NAD-dependent deacetylases (ySir2: IC50=48µM; hSIRT1: IC50=60µM; hSIRT2: IC50=58µM) with no effect on human HDAC1. Reported to inhibit Sir2p transcriptional silencing activity in vivo (IC50=25µM) and NAD-dependent histone deacetylase activity of purified recombinant yeast Sir2p (IC50=70µM) and hSIRT2 (IC50=40µM) in vitro.

Formule: C₂₆H₂₂N₂O₂
Poids moléculaire: 394,46 g/mol
Numéro CAS: 410536-97-9
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